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Mitochondrial DNA (mtDNA) Analysis

The majority of the human genome is located within the nucleus of the cell. There is however another type of DNA called mitochondrial DNA (mtDNA) located in structures outside the nucleus called mitochondria. mtDNA, unlike nucDNA (half mother/half father) is inherited from the mother only. mtDNA analysis is especially vital to forensic identification cases when the amount of DNA present is very minute, the biological sample is old or degraded and/or only distant maternal references are available for comparison purposes. The analysis process targets the hypervariable regions of mitochondrial DNA utilizing BigDye® Terminator Cycle Sequencing.

mtDNA tests offered by Mitotyping Technologies, LLC:

  • Hypervariable Regions I and II
  • Mini Primer Sets
  • Variable Regions 1 and 2
  • 12S Species Determination
  • mtDNA Analysis of Domestic Dogs (Canine Species)

Our very own Terry Melton and Charity Holland are considered experts in the field of mitochondrial DNA. You can learn more about their experience through our staff biography pages.